 | ThermonucleotideBLASTThermonucleotideBLAST is an application for searching a target database of nucleic acid sequences. |
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ThermonucleotideBLAST Ranking & Summary
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- License:
- GPL
- Price:
- FREE
- Publisher Name:
- Jason D. Gans
- Publisher web site:
- http://public.lanl.gov/jgans/tntblast/
ThermonucleotideBLAST Tags
ThermonucleotideBLAST Description
ThermonucleotideBLAST is an application for searching a target database of nucleic acid sequences. ThermonucleotideBLAST is an application for searching a target database of nucleic acid sequences using an assay specific query that is based on biochemical assays (i.e. a pair of oligonucleotide sequences representing PCR primers or Padlock probes, a triplet of oligos representing PCR primers and a TaqMan probe, or a single oligo representing a hybridization probe).Unlike existing programs like BLAST, which use heuristic measures of sequence similarity for identifying matches between a query and target sequence, ThermonucleotideBLAST uses free energy and melting temperature.What's New in This Release:· This update features a significant rewrite of thermodynamic alignment algorithm, including the addition of the Dinkelbach fractional programming algorithm for computing duplex melting temperatures.
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