Percolator

A proteomics post processor to help you with your work.
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Percolator Ranking & Summary

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  • Rating:
  • License:
  • Apache License 2.0
  • Publisher Name:
  • Lukas K?ll
  • Operating Systems:
  • Windows NT / 2K / XP / Vista
  • File Size:
  • 598 KB

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Percolator Description

Percolator is a simple and easy-to-use tool that will provide users with a proteomics post processor. The first step in analyzing an mass spectrometry assay is to match the harvested spectra against a target database using database search engines such as Sequest and Mascot, a process that renders list of peptide-spectrum matches. However, it is not trivial to assess the accuracy of these identifications. Percolator uses a semi-supervised machine learning to discriminate correct from incorrect peptide-spectrum matches, and calculates accurate statistics such as q-value (FDR) and posterior error probabilities.


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